Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension
نویسندگان
چکیده
منابع مشابه
Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension.
AIMS Elevated levels of pro-inflammatory cytokine interleukin-17A (IL-17) are associated with hypertensive autoimmune diseases; however, the connection between IL-17 and hypertension is unknown. We hypothesized that IL-17 increases blood pressure by decreasing endothelial nitric oxide production. METHODS AND RESULTS Acute treatment of endothelial cells with IL-17 caused a significant increase...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2012
ISSN: 1755-3245,0008-6363
DOI: 10.1093/cvr/cvs422